Peripheral Artery Disease

One in every 20 Americans over the age of 50 has Peripheral Artery Disease (PAD), a condition that raises the risk for heart attack and stroke. Peripheral artery disease is known by many names, but is often just called "PAD". An older term that is sometimes used is "peripheral vascular disease (or "PVD"). The term PVD, like other general terms (e.g., "poor circulation"), is not specific to diseases that block blood flow in an artery.

PAD is a form of "atherosclerosis" that is caused when the arteries in your leg become slowly narrowed and blocked as a consequence of age, smoking, high blood cholesterol, high blood pressure or diabetes. A family history of PAD can also increase personal risk.

PAD often occurs without symptoms, but in some individuals causes exertional discomfort or pain in the muscles, called "claudication". This type of muscle discomfort is reproducible with exercise and does not occur at rest.

Click on the video below to learn more about PAD:


Click on the link below to read an informative PAD fact sheet developed by US Department of Health and Human Services and the National Heart, Lung and Blood Institute, part of the National Institutes of Health (PDF):

PAD fact sheet - Click Here for Brochure

To find out more about participating in a CCTRN PAD study, the PACE trial, click here.