The mission of the Coordinating Center for Clinical Trials (CCCT) is the
coordination of large multi-center controlled clinical trials. The goal of the
Center is to identify important public health problems and design large clinical
trials to study the efficacy of appropriate interventions, including the
collection, management, reporting, and interpretation of study findings.
The goals of the Center are to identify important health problems; design large
clinical trials to study the efficacy of appropriate interventions; collect,
report and interpret study findings; and contribute to medical, statistical, and
clinical trials knowledge.
Research areas of the Center:
- Hypertension - detection, treatment and outcomes
- Hypercholesterolemia - detection, treatment, and outcomes
- Genetics of hypertension
- Cost-effectiveness of hypertension and hypercholesterolemia
- Heart failure - detection and validation
- Long-term natural history of retinopathy of prematurity (ROP)
- Effects of cryotherapy ROP on outcome of patients with ROP
- Effects of earlier treatment with retinal ablative therapy for ROP
- Long-term ophthalmological outcomes in premature infants treated with retinal
ablative therapy for ROP
- Screening for ROP
- Health related quality of life in children who were premature
- Development and application of risk model in the management of ROP
- Stopping rules in clinical trials
The Research Data Repository System (RDRS) is a web-based application used for allowing easy
and secure access to research data within the Coordinating Center For Clincial Trials. The system provides access to the data bases for
all prior research studies. Through a series of web applications, the data
dictionaries for these studies are used to present data through dynamically
generated web forms, statistical applications such as Crosstab reports and allow
easy extraction of these data into statistical applications such as SAS, SPSS
and Stata which can be used for more advanced statistical techniques.